CD27 Antikörper

Produktnummer ABIN7670002

Der Maus Monoklonal Anti-CD27-Antikörper wurde für FACS validiert. Er ist geeignet, CD27 in Proben von Human zu detektieren.

Kurzübersicht für CD27 Antikörper (ABIN7670002)

Target: CD27 (CD27 Molecule (CD27))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD27 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: O323

Produktdetails anti-CD27 Antikörper

Verwendungszweck: Purified Anti-Human CD27 Antibody[O323]

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: avoid freeze / thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Haltbarkeit: 12 months

Details zu CD27

Target: CD27 (CD27 Molecule (CD27))

Andere Bezeichnung: CD27

Hintergrund: S152. LPFS,T-cell activation antigen CD,TNFRSF,S152.LPFS,CD27,S152,S152. LPFS2,T14,TNFRSF7,Tp55,S152.LPFS2,CD27L receptor,T-cell activation antigen CD27, S152, TNFRSF7,CD 27,CD27 antigen,CD27 Molecule,LPFS2,MGC20393,OTTHUMP00000238557,T cell activation antigen CD27,T cell antivation antigen S152,TNFRSF 7,TNFSF7,Tp 55,Tumor necrosis factor receptor superfamily member 7,The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

UniProt: P26842

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints